glutathione and tamoxfen Enhanced mitochondrial metabolism: A new mechanism for driving Product Type:1000 Capsules

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GSH depletion causes ferroptosis in RPE cells To evaluate the mechanism of cell death in GSH-depleted cells, we treated RPE cells with various cell death pathway inhibitors including ferroptosis inhibitors ferrostatin-1 (Fer-1, 8 μM), liproxstatin-1 (Lip-1, 600 nM), iron chelator deferoxamine (DFO, 80 μM), pan-caspase inhibitor z-VAD-fmk (30 μM) to inhibit apoptosis, autophagy inhibitor 3-methyladenine (3-MA, 10 mM), and lysosomal inhibitor bafilomycin A1 (Baf-A1, 75 nM)

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Product Type:1000 Capsules

[DOI] [Google Scholar] 51.Silva J.R.R., Fernandes A.R., Silva Junior M.L., Santos C.R.C., Lobato A.K.S.J.P