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Microglial self-defence mediated through GLT-1 and glutathione | Amino Acids | Springer Nature Link
In a model of Aβ-induced neuronal injury, lycopene did not activate NF-κB, p65, or TLR4 expression (Tripathi et al., 2018), but restored mitochondrial morphological membrane potential and ATP levels (Qu et al., 2016) and inhibited Bax and mitochondria
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However, milder variants occasionally present later in life, requiring specialized genetic testing to differentiate from B12 deficiency
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