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A major benefit of implementing an in silico approach to investigating quinone metabolism is the ability to simulate and visualise radical species, such as superoxide, in real time, as this is essentially inaccessible experimentally both in vitro and in vivo

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Additionally, research showed that in ESRD patients using supplements, the risk of death and CVD increased by 7% and 9%, respectively, with every significant rise in homocysteine concentration of 5 mmol/L