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[55] provided experimental evidence to demonstrate the competing roles of CYPs and AKRs in the metabolic activation of (+/−)-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene (BP-7,8-diol) in human bronchoalveolar H358 cell extracts
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[11] Two magnesium ions function to stabilize the acylphosphate intermediate, facilitate binding of ATP, and activate removal of phosphate group from ATP
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