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Further, when discussing a cyclic test, Hucks states, "It failed after 223,700 cycles, a value typical of pipe performance." From the prior charts, we can see cycles exceeding 20 to 50 or more per day to be realistic expectations resulting in a life expectancy of roughly only 30 years

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However, new strategies that focus on some of the novel molecular initiating events described earlier as potential therapeutic targets are currently under investigation