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The cholesterol derivative 27-hydroxycholsestrerol, produced primarily by the enzyme CYP27A1, promotes tumor progression by increasing the number of polymorphonuclear neutrophils and γδ-T cells while decreasing the number of cytotoxic CD8+ T cells, which facilitates breast cancer metastasis
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[DOI] [PMC free article] [PubMed] [Google Scholar] 334.Khanijou V, Zafari N, Coughlan MT, MacIsaac RJ, Ekinci EI
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