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Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets - PMC
The pair-feeding methodology is what makes this paper unusual Most rat studies stop at "the drug caused weight loss." Petersen went further with two control designs that are worth understanding, because they are the source of every honest claim you can make from this paper
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Barrier function, tissue integrity, immune signaling, and the gut's broader relationship with systemic physiology are all deeply interconnected - which means the most meaningful research questions tend to involve multiple systems at once
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