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[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Mikus D, Sikiric P, Seiwerth S, Petricevic A, Aralica G, Druzijancic N, et al
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A canonical example of such behavior is provided by dimeric transcription factors, where dominant-negative mutations preserve dimerization and DNA binding but disrupt the transcriptional activation domain, such that WT/mutant heterodimers bind DNA normally yet are defective in transcriptional activation 58
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