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Data availability The bulk transcriptome of the PDAC tissues generated in this study has been deposited in the Genome Sequence Archive (GSA) database under accession code HRA017653 [ The untargeted metabolome of the PDAC tissues generated in this study has been deposited in the NODE database under accession code OEZ00021697 [ ATAC-seq for GLUL-KO and -WT Thp-1 cells were deposited in the GSA database under accession code HRA018391 [ External public PDAC datasets of bulk transcriptome were derived from TCGA ( ArrayExpress ( (ID: E-MTAB-6134), and GEO (ID: GSE71729, GSE57495, GSE85916)
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4b) whereas the chylomicron TG clearance was increased (Fig
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