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Lipid metabolites such as linoleic and γ-linolenic acids were downregulated during NH₃-N stress, reflecting their utilization in combating oxidative damage and maintaining energy balance ( Dicentrarchus labrax and Verasper variegatus suggest lipid metabolism as a central pathway in mitigating ammonia toxicity Lipid metabolism is a key regulatory pathway for aquatic animals under environmental stress, supplying essential fatty acids, energy, and supporting immune responses (Lee et al., 2018)
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