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Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets - PMC

As expected, in RBCs exposed to 20 mM H 2 O 2 for 1 h at 25°C, the intracellular ROS content was significantly higher than that of control RBCs, whereas the anthocyanin extract (0.01 μg/mL) alone did not affect the production of intracellular ROS (data not shown)

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The mechanisms of MSM’s antioxidant activity includes increasing the activity of superoxide dismutase [6,8,20,30–32], enhancing total antioxidant capacity (TAC) [6–8,10,33,34], reducing malondialdehyde (MDA) [8,10,12,13,20,31,32,35], and regulating the glutathione system (e.g., glutathione synthesis and glutathione peroxidase activity) [7,8,13,20,32,35]