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These therapies display higher efficiency compared to classical senolytic drugs (BCL-2 or tyrosine kinase inhibitors) but for some of them, such as NA + /K + ATPase inhibitors, clinical development could be complex in the light of strong cardiotoxicity associated with this class of molecules
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doi: 10.1146/annurev.cellbio.17.1.25 [DOI] [PubMed] [Google Scholar] 29.De Palma L, Marinelli M, Memè L, Pavan M
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