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In contrast, immunosuppressive M2 macrophages rely on oxidative phosphorylation and fatty acid oxidation, exhibiting altered PC remodeling and reduced phospholipid turnover that favor tissue repair and tumor tolerance
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Measurement:10 kg
In AML cell lines and primary blasts, CB-839 decreased cell viability, blocked glutamine use, and sensitized leukemic cells to priming with venetoclax (29)
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