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As discussed, the mechanisms of uptake of HMCDs across the BBB and into the tumor cells are unclear
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Lentivirus, siRNA, plasmid construction, and cell transfection Lentiviral vector containing human full-length circCDK13, the mutant version of circCDK13 (the sequence of “ACAAACA” was replaced with “UGUUUGU”), as well as their corresponding negative control were purchased from Geneseed (Guangzhou, China)
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