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PDF) Topically applied GHK as an anti-wrinkle peptide: Advantages, problems and prospective
Amico-Roxas M, Caruso A, Cutuli VM, et al
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Half-life & pharmacokinetics In rats, dihexa's terminal half-life was reported as approximately 12.68 days after intravenous administration and approximately 8.83 days after intraperitoneal administration — extraordinarily long for a molecule of 505 Da, and attributed to a very large volume of distribution with slow release from tissue rather than to slow metabolism per se
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