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34 Fenton reaction and lipid peroxidation in hepatotoxicity According to a more recent review by Dixon and Stockwell, 35 there are “ three essential hallmarks that define ferroptosis: the loss of lipid peroxide repair capacity by the phospholipid hydroperoxidase GPx4, the availability of redox-active iron, and the oxidation of PUFA-containing phospholipids .” Although the term ferroptosis is new, the process of iron-dependent lipid peroxidation (LPO) as a mechanism of cell death in the liver has been recognized for 60 years

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participation on a Data Safety Monitoring Board or Advisory Board with the NIH-funded study “Health Options”, German National Committee on the “Future of Public Health Research and Education”, EDCTP Evaluation, UNAIDS Evaluation Expert Advisory Committee, National Institute of Health Study section member on Population and Publica Health Approaches to HIV/AIDS (PPAH), US National Academies of Sciences, Engineering, and Medicine’s Committee for the “Evaluation of Human Resources for Health in the Republic of Rwanda under the President’s Emergency Plan for AIDS Relief (PEPFAR)”, University of Pennsylvania (UPenn) Population Aging Researching Center (PARC)