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edta and glutathione Assessment of GSSG by the EDTA-modified NADPH/glutathione reductase Type:55g
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Meanwhile, hypoxia-induced FAO impairment in tubular cells exacerbates lipid accumulation and ferroptosis, while fibrosis itself creates a pathological microenvironment—compressing renal microvessels to sustain hypoxia and trapping inflammatory cells to perpetuate inflammation—thus closing the loop and reinforcing the ferroptosis–inflammatory–hypoxic–fibrotic cascade
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