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These factors contribute to the development of diabetic vascular complications, including diabetic retinopathy (a leading cause of blindness), nephropathy, other sensorial damage, and cardiovascular diseases [8,9,10]

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Real-time PCR analysis of Gif expression across different tissues showed that Gif expression was restricted to the stomach of WT mice, and this was abolished in Gif –/– (F1) mice (Figure 1A)