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A GSL Switch is Unlikely in the Current Climate Despite a recent drive by the Department of Health and Social Care (DHSC) to encourage the reclassification of certain medicines (like those for pain, sleep aids, and skin conditions) to P or GSL status, a switch for injectable B12 is not on the cards
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⛔Contraindications •No formal contraindications established (no human studies) •Theoretical concern for individuals with NNMT-dependent cancers •Theoretical concern for pregnancy/lactation (no reproductive toxicity data) ⚠️Drug Interactions •No drug interaction studies have been conducted •Theoretical interaction with medications affecting methylation pathways •Theoretical interaction with NAD+ precursors (NMN, NR) -- unstudied Community-Reported Side Effects See which side effects community members report most frequently
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