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Retatrutide , a triple agonist targeting GIP, GLP-1, and glucagon receptors, is still available through some research vendors, though Eli Lilly (also its developer) may eventually extend enforcement to this compound as well

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It promotes resolution of inflammation by shifting macrophage activity from a pro-inflammatory (M1) phenotype toward a reparative (M2) phenotype, thereby effectively reducing fibrosis and promoting enhanced tissue regeneration [11, 23, 26, 50]