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Notably, impairing γ-glutamylcysteine biosynthesis in the cytosol, but not in mitochondria, still allowed γ-glutamylcysteine to efficiently detoxify ROS
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Coupling of the WLP to butyrate formation is proposed as a means by which relatively low flux through both pathways is sufficient to regenerate substantial amounts of NAD + to support the fermentation of carbohydrates
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