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This self-reinforcing CPT1A/c-Myc signaling circuit establishes robust ferroptosis protection in cancer stem cells through dual mechanisms: bolstering the cellular antioxidant defense via NRF2-mediated GPX4 upregulation and limiting peroxidation-susceptible phospholipid pools through ACSL4 suppression (38)
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doi: 10.1111/j.1365-2036.2004.01881.x
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