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The recommended daily dose of vitamin E is 15 mg (30 IU) for adults [173], a dose of 200–800 mg/day may cause gastrointestinal distress, while a daily dose greater than 1000 mg (1500 IU) is associated with increased risk of hemorrhage (antiplatelet effects), thrombophlebitis,, elevated creatinine, gonadal dysfunction and death [163, 174]
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