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Molecular models of the FOXO4:p53-DBD and FOXO4-DRI: p53-DBD complexes.... | Download Scientific Diagram
INTRODUCTION Obesity rates have escalated in the past few decades, expanding from a condition affecting only a minor proportion of the adult populations of industrialized nations, into a global pandemic
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In summary, the GH/IGF-1 axis regulates mitochondrial (intrinsic)-mediated apoptosis mostly via activation of the PI3K-AKT/FOXO pathway and possibly via cell-specific transcriptional regulation of antiapoptotic genes
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