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To test these hypotheses, aged (22-month-old) mice were separated into Sed and PoWeR groups, which were further subdivided into cohorts that received once-daily dosing of saline (control) or NNMTi (5-amino-1-methylquinolinium [5A-1MQ]) for eight weeks
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Leukocytosis, thrombocytosis, eosinophilia, anemia, macrocytosis, or an abnormal blood smear alongside persistent elevation should prompt hematology review
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