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Fatty Aldehyde and Fatty Alcohol Metabolism: Review and Importance for Epidermal Structure and Function - PMC
Ethylmalonic aciduria secondary to ETHE1 dysfunction (OMIM# 602473) Ethylmalonic encephalopathy (EE) is a rare, devastating, invariably fatal neurodegenerative disease caused by mutations in the ETHE1 gene, which encodes a mitochondrial sulfur dioxygenase critical in hydrogen sulfide (H 2 S) detoxification [147]
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Complex I (site I Q ) and Complex III (site Q o ) are subjected to single-electron leakage under conditions of high membrane potential or reverse electron transport (RET), directly reducing O 2 to •O 2 − in mitochondria (Fig
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