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[DOI] [Google Scholar] 188.Liang P.Z., Li L., Zhang Y.N., Shen Y., Zhang L.L., Zhou J., Wang Z.J., Wang S., Yang S

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Compound 77 demonstrated functional inhibition of PDE10A with a Ki value of 0.029 nM and over 500,000-fold selectivity over other PDE enzymes, making it a promising PDE10A inhibitor (Figures 22A,B)