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2.6 Crosstalk between ferroptosis and other cell death modalities Ferroptosis does not occur in isolation but forms an intricate cell death network with other regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, and the recently identified cuproptosis
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The PI3K antagonist phosphatase and tensin homolog (PTEN) is a tumor suppressor that counteracts growth factor-dependent mTORC1 activation by dephosphorylating PIP3 to generate PIP2 (reviewed by Laplante et al
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