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Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs - PMC
194 The pathophysiology is thought to involve ischemia due to microangiopathy and metabolic disturbances
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PKC activation disrupts normal metabolism, leading to ATPase phosphorylation and metabolic disorders, including changes in VEGF and vasoconstriction, which affect pain perception
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