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This review elaborates on the mechanism of TCM treatment for HPAG based on cellular signalling pathways, which reflects the flexibility of TCM in treating diseases and the advantages of multi-level, multi-pathway, and multi-target treatments for HPAG
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As GPX4 has traditionally been thought of as resistant to limited Se pools, this finding indicates that the selenoprotein hierarchy may be altered in cancer cells, resulting in an overreliance on GPX4
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