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The increase in IL-1 related to hs-CRP (High Sensitivity C-reactive protein), a protein linked to a cardiovascular risk factor, together with the increase in free radicals is among the trigger points of toxicity induced by doxorubicin, in addition to the alteration of intracellular calcium homeostasis
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doi: 10.1101/cshperspect.a033118 3 GBD 2016 Neurology Collaborators
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