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Side Effects Common Side Effects: Usually, mild and temporary reactions may include: Mild pain at the injection site Nausea or stomach discomfort Headache Dizziness Serious & Rare Side Effects: Rarely, some patients may experience: Allergic reactions (rash, itching) Swelling or breathing difficulty Severe hypersensitivity reactions Irregular heartbeat (very rare) 👉 Most side effects of Methylcobalamin injection are mild and resolve quickly