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More than a dozen genes, including SNCA , LRRK2 , GBA , PINK1 , PRKN , DJ-1 , and ATP13A2 , have been implicated in PD pathogenesis, many of which are directly involved in mitochondrial function and ROS detoxification (260–262)
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There are three isoforms of NOS: neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) [50]
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