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However, the isoform A (exon 11-splice variant) of IR (IR-A), normally expressed in fetal tissues, promotes cell growth in response to IGF-2 stimulation and has been reported to be abundantly expressed in some IGF-1R deficient leiomyosarcomas (Sciacca et al, 2002)
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10.3390/ijms19010011 [DOI] [PMC free article] [PubMed] [Google Scholar] 79.Russo SJ, Charney DS
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