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Genetic factors and prenatal conditions contribute to the co-occurrence of IBD and ASD 17,18
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71, 72 Considering that the amino acids derived from glutamine are the ones obtained from Oaa and Akg, which are also intermediates of the TCA cycle, what is the physiological advantage for cancer cells to synthesize amino acids using glutamine by reductive carboxylation as compared with normal cells that derive them by using skeleton carbon from glucose and amino groups from glutamine
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