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PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells - Journal of Biological Chemistry
For example, the primary outcome is the 24-hour PTR, as opposed to other markers of RBC destruction, such as indirect bilirubin or iron parameters, which may correlate better with hemolysis in vivo (54)
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“Finding that interesting loop later led to our understanding of the sensing mechanism,” Birsoy says
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