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Heme depletion Heme, essential for oxygen transport, cellular respiration, and gene regulation, is mainly produced by erythroblasts and hepatocytes

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no controlled human trial Cycle length 8–12 weeks How it is usually described Extended plan for slower or longer research timelines Evidence note Less consistent and supported by even less safety data Cycle length More than 12 weeks How it is usually described Long-term or repeated use Evidence note No established human safety basis for the combined stack The calendar alone cannot show whether tissue has recovered or whether continued exposure is safe