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In addition, studies have shown that the introduction of D-tyrosine into the N-terminal or C-terminal of pentapeptide-18 can reduce the melanin content by 50% at 500 μM, the tyrosinase activity by 18% at the N-terminal and by 25% at the C-terminal

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SF affects one carbon (1C) metabolism in HepG2 cells We next quantified glycine and serine and found that SF decreased both the serine and glycine intracellular pool (Fig